|
Ciclosporin A |
(Biochemistry) |
| | |
| | 
|
| Investigation | : |
Ciclosporin A | |
| Specimen type | : |
Whole Blood |
| Spec container | : |
EDTA
|
| Volume required | : |
4 mL |
| Reference range | : |
see below |
| Turnaround | : |
<72 hours |
|
|
|
|
Ciclosporin is also a calcineurin inhibitor and it's interpretation is complex. Trough levels may vary depending on the clinical scenario, such as illness or type of transplant, concomitant immunosuppression, time post-transplant and dosage regime.
For further information the appropriate clinical team/s looking after the patient should be contacted
As a guide for interpretation of ciclosporin levels see suggested thresholds from the Post-Operative Care in the Kidney Transplant Recipient BTS/UKRA Guidelines 2017:
- Ciclosporin can be monitored by either C0 (Trough) or 2 hour post dose (C2)
- High, medium and low trough (C0) levels for ciclosporin are: >200, 100-200 and <100 ug/L
- An additional consideration is that mistiming of sampling in relation to medication can cause unexpected high/low levels of ciclosporin and are not true trough levels
See TDM information.
| ICE requesting info: | ICE panel name | ICE page name | Column | Comment\Advice |
|
Chem / Haem |
Drug |
1 |
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